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Table 3 Multiple regression predictive models (A) and analyses of variance of haplotypes (B)

From: Nuclear genomic control of naturally occurring variation in mitochondrial function in Drosophila melanogaster

Trait

Analysis

Variable

SNP Location

Estimate

t

P-value

  

Intercept

--

2009.79

55.49

<0.0001

ST3

Sex Average

3L _651118

Gale (u3)

−290.43

−5.56

<0.0001

 

r2 = 0.666

3R _18209173

CG31169 (cds)

209.42

−5.78

<0.0001

  

Intercept

--

237.31

44.29

<0.0001

ST4

Sex Average

3R _16981874

SNF4Agamma (in)

−15.71

−5.08

<0.0001

 

r2 = 0.686

2R _3529122

CG43340 (#)

18.15

5.84

<0.0001

  

Intercept

--

2.693

124.52

<0.0001

P:O ratio

Sex Average

2L _18554474

Pde11(in)

0.046

3.71

0.0007

 

r2 = 0.744

3L _2682962

CG12187(in)

−0.070

−5.12

<0.0001

  

3L _9640097

fry(in)

−0.053

−3.90

0.0004

B

Trait

Analysis

Source of Variation

df a

MS b

F

P -value

σ 2 c

  

Haplotype

3

13648093

24.3

<0.0001

144977

ST3

Sex Average

Line (Haplotype)

36

577585

1.9

0.0014

19080

  

Error

535

302190

--

--

302038

  

Haplotype

3

127247

22.4

<0.0001

677.3

ST4

Sex Average

Line (Haplotype)

36

5689

1.3

0.1430

84.7

  

Error

535

4498

--

--

4495.6

  

Haplotype

6

1.26

21.8

<0.0001

15.0

P:O ratio*

Sex Average

Line (Haplotype)

33

0.06

0.9

0.6922

0.0

  

Error

505

0.07

--

--

67.0

  1. Markers are listed in the order in which they are entered in the model. Estimates of effects are for (Minor allele – Major allele). ST3, mitochondrial State 3 respiration; ST4, mitochondrial State 4 respiration. In, intronic; cds, coding sequence; #, missense; u3, 3’ UTR. aDegrees of freedom. bMean Squares computed from Type III Sums of Squares. cRestricted maximum likelihood estimates of variance component . * σ2 multiplied by 103.