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Figure 5 | BMC Genomics

Figure 5

From: Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4

Figure 5

Characterization of different response types by integration of cistromic and genome-wide expression profiling analysis. (A) Comparison of PPARβ/δ occupancy of the 203 direct target genes between the different response types. PPARβ/δ occupancy is shown without (blue dots) and with (red dots) exogenous ligand (GW0742) in relation to the TSS. Relative expression of the target genes in wild-type (+/+) and Pparβ/δ-null (−/−) samples is shown in the heat map to the right of this analysis. (B) Relative distribution of PPARβ/δ occupancy in the absence or presence of exogenous ligand for the different response types. (C) The distribution of PPARβ/δ occupancy in relation to the TSS for the direct target genes for the four major response types.

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