Skip to main content

Table 1 Enriched molecular functions of compared Drosophila melanogaster maternal genes

From: Identification of maternally-loaded RNA transcripts in unfertilized eggs of Tribolium castaneum

Group

GO term

P-value

Sample frequency

Background frequency

A

small molecule binding (GO:0036094)

5.17e-08

525/3235 (16.2%)

552/3718 (14.8%)

 

nucleoside phosphate binding (GO:1901265)

1.24e-07

486/3235 (15.0%)

510/3718 (13.7%)

 

nucleotide binding (GO:0000166)

1.24e-07

486/3235 (15.0%)

510/3718 (13.7%)

 

organic cyclic compound binding (GO:0097159)

1.24e-07

486/3235 (15.0%)

510/3718 (13.7%)

B

sequence-specific DNA binding transcription factor activity (GO:0003700)

5.44e-04

35/184 (19.0%)

290/3718 (7.8%)

 

nucleic acid binding transcription factor activity (GO:0001071)

5.44e-04

35/184 (19.0%)

290/3718 (7.8%)

 

structural constituent of chitin-based cuticle (GO:0005214)

4.36e-03

11/184 (6.0%)

41/3718 (1.1%)

 

structural constituent of cuticle (GO:0042302)

7.28e-03

11/184 (6.0%)

43/3718 (1.2%)

C

endopeptidase activity (GO:0004175)

6.26e-10

37/299 (12.4%)

124/3718 (3.3%)

 

serine-type endopeptidase activity (GO:0004252)

5.99e-09

21/299 (7.0%)

45/3718 (1.2%)

 

peptidase activity, acting on L-amino acid peptides (GO:0070011)

8.20e-08

41/299 (13.7%)

171/3718 (4.6%)

 

serine-type peptidase activity (GO:0008236)

4.22e-07

21/299 (7.0%)

54/3718 (1.5%)

  1. The four enriched molecular function terms with the lowest p-values for each group within the comparison of the Berkeley Drosophila Genome Project in situ database maternal genes to the T. castaneum findings. Group A consists of D. melanogaster maternal genes with T castaneum maternally loaded orthologs. Group B consists of D. melanogaster maternal genes with T. castaneum orthologs which were expressed in fertilized eggs but not maternally loaded. Group C consists of Drosophila melanogaster maternal genes with T. castaneum orthologs which were not expressed in eggs.