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Figure 5 | BMC Genomics

Figure 5

From: A parallel genome-wide mRNA and microRNA profiling of the frontal cortex of HIV patients with and without HIV-associated dementia shows the role of axon guidance and downstream pathways in HIV-mediated neurodegeneration

Figure 5

Significantly down-regulated genes on MAPK pathway in HAD brains compared to HIV non-dementia brains. Pathway analysis has revealed the significant involvement of MAPK pathway in HAD brains. The genes, which were found to differentially express between HAD versus non-demented patients in the current study are highlighted in green. The rectangles represented members of Mitogen-activated protein kinases family while the ovals are related genes involved in MAPK pathway.

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