Table 2 Effect of a chronic Western diet on the expression of genes related to cholesterol and lipid metabolism in the small intestine ^a

Abca1

ATP-binding cassette, sub-family A, 1

-1.13

0.466

Abcg5

ATP-binding cassette, sub-family G, 5

-1.48

0.006

Abcg8

ATP-binding cassette, sub-family G, 8

-2.35

0.002

Acaa2

acetyl-Coenzyme A acyltransferase 2

1.67

0.010

Apoa2

Apolipoprotein A-II

3.15

0.001

Apoc2

Apolipoprotein C-II

1.36

0.006

Cav1

Caveolin 1

1.6

0.006

CD36

CD36 antigen

2.11

0.020

Ces1d

Carboxylesterase 1D

-6.13

< 0.001

Ces1g

Carboxylesterase 1G

-5.46

< 0.001

Cpt1a

Carnitine palmitoyltransferase 1a, liver

1.55

0.044

Cyp27a1

Cytochrome P450, family 27, subfamily a, polypeptide 1

-2.57

0.004

Cyp51

Cytochrome P450, family 51

2.03

0.001

Dhcr7

7-dehydrocholesterol reductase

1.48

0.011

Hmgcl

3-hydroxy-3-methylglutaryl-Coenzyme A lyase

1.57

0.024

Hmgcr

3-hydroxy-3-methylglutaryl-Coenzyme A reductase

1.02

0.748

Hmgcs2

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2

8.07

< 0.001

Hsd17b7

Hydroxysteroid (17-beta) dehydrogenase 7

1.32

0.045

Idh1

Isocitrate dehydrogenase 1 (NADP+), soluble

1.31

0.010

LDLr

LDL receptor

4.29

< 0.001

LXRα

Liver × receptor alpha

1.77

0.003

LXRβ

Liver × receptor beta

-1.06

0.646

Me1

Malic enzyme 1, NADP(+)-dependent, cytosolic

3.13

< 0.001

Mttp

Microsomal triglyceride transfer protein

1.18

0.016

Mvd

Mevalonate decarboxylase

1.33

0.012

Mvk

Mevalonate kinase

1.22

0.017

Npc1l1

Niemann-Pick C1-like protein 1

-2.02

< 0.001

Nsdhl

NAD(P) dependent steroid dehydrogenase-like

1.45

0.004

Pcsk9

Proprotein convertase subtilisin/kexin type 9

1.65

0.007

Pmvk

Phosphomevalonate kinase

2.46

< 0.001

Scarb1

Scavenger receptor class B, member 1

1.4

0.447

Scd1

Stearoyl-Coenzyme A desaturase 1

90.7

< 0.001

Scd2

Stearoyl-Coenzyme A desaturase 2

6.50

< 0.001

Slc25a1

Solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1

2.04

< 0.001

Slc27a4

solute carrier family 27 (fatty acid transporter), member 4

-1.12

0.209

Sqle

Squalene epoxidase

2.11

0.011

Srebp-2

Sterol regulatory element binding factor 2

1.59

0.004

Tm7sf2

Transmembrane 7 superfamily member 2

1.52

0.003