Figure 2

Aggregation Propensity Plots for HCHA_ECOLI. The plot shows the aggregation propensity on a scale of 100 and its variation along the amino acid sequence of respective protein. The points corresponding to peaks on graph signifies aggregation prone region on graph. The generation of new peaks or increase in pre-existing peaks can be seen after mutation with hydrophobic residues showing greater propensity to aggregate. (X axis = amino acid residue number; Y-axis = aggregation propensity on scale of 100).