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Table 4 Cellular functions/processes affected by genes required for resistance to EcoRI

From: A multistep genomic screen identifies new genes required for repair of DNA double-strand breaks in Saccharomyces cerevisiae

Function or process

Genes

Sister chromatid cohesion

CTF4, CTF8, DCC1, HTL1

Histone modification/remodeling

ARP5, EAF1, GCN5, RTT109(REM50)b, SPT10, UBP8

Nuclease processing of DNA

EXO1, MMS4, SAE2, YLR235C/TOP3 a

Chromosome stability/segregation

BIK1, CGI121, CNM67, DDC1, MMS22

Transcription regulation

APQ13/NET1a, BUD32, BUR2, CCR4, NOT5, NUP84, RPB9, BUD30/RPC53a, RTF1, SFP1, SPT20, TAF14, UME6, YML009W-B/SPT5a

RNA processing/modification

CDC40, LRP1, LSM7, TRM9, TSR2/YLR434Ca, YDR433W/NPL3a

Protein posttranslational modification

AKR1, BCK1, CAX4, MMS2, OCH1, RAD5, UBR1,

 

YML012C-A/UBX2 a

Cell membrane/cell wall

CIS3, HSP150, RVS161, SAM37, VMA7, VPH2/YKL118W a

Mitochondrial proteins

ATP2, IMG2, MCT1, YGL218W/MDM34 a , MRPS35, RSM7/YJR114W a , SCO1

  1. a Gene names separated by a forward slash indicate deletions within two overlapping open reading frames. Functions and processes are described for the verified gene only. Source: The Saccharomyces Genome Database.
  2. b The RTT109 gene is frequently referred to as REM50 in the literature.