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Figure 1 | BMC Genomics

Figure 1

From: 5′ tRNA halves are present as abundant complexes in serum, concentrated in blood cells, and modulated by aging and calorie restriction

Figure 1

Length distribution of reads obtained by deep sequencing of small RNAs extracted from mouse serum. Shown here are only those reads that map to the mm10 (GRCm38) mouse genome. (A) Length distribution is displayed by abundance of sequencing reads combined from 9 serum samples. Reads were mapped to the mouse genome with bowtie according to Maq’s default policy, either allowing (blue bars) or disallowing (red bars) multiple reportable alignments for each read. (B) Combined reads were mapped to the mouse genome with bowtie according to the end-to-end k-difference policy, either allowing (blue bars) or disallowing (red bars) multiple reportable alignments for each read. (C) Length distribution of separate sequencing reads obtained from 9 individual serum small RNA samples. Length distribution is displayed by abundance of sequencing reads that were mapped to the mouse genome with bowtie according to Maq’s default policy, and allowing multiple reportable alignments for each read. Bars with different colors denote the source of the sequenced serum small RNA from the 9 different samples.

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