Figure 1

Correlation between 300-bp paired end reads and 3-kbp mate pair reads. (A) The coverage measured using the 300-bp paired end reads was correlated with the 3-kbp mate pair reads. While the scatterplot illustrates 100,000 randomly selected points in the dataset, the linear regression was calculated on the entire data set revealing a significant correlation with a p-value of <2e-16, an intercept of 0.61, a slope of 8.2, and an R-squared value of 0.77. (B) Overlaying the coverage calculated with the paired end reads (blue) and the mate pair reads (orange) across 20-kbp of the Brugia genome shows how the peaks and troughs in both are nearly identical.