Figure 2

CAMP factor encoding loci of the P. acnes genome are absent from the P. avidum genome. A) CAMP factor 1 (PPA1340) in the P. acnes KPA genome is encoding within a gene cluster, that is replaced by a different cluster in P. avidum. Adjacent genes to this gene cluster are conserved in both genomes. Same color and number depicts homologs. B) CAMP factor 2 (PPA0687) of P. acnes is clustered with five other genes, encoding sialidases and a sialic acid transporter. This gene cluster is absent in the genome of P. avidum. C) CAMP factor 4 (PPA1231) and three adjacent genes of P. acnes KPA are replaced in the genome of P. avidum by a larger gene cluster. P. avidum ATCC25577 was used for this illustration; the genome of P. avidum TM16 is identical in the depicted genomic regions.