Skip to main content

Table 3 Representative cytokines regulated by FGF2

From: FGF2-induced effects on transcriptome associated with regeneration competence in adult human fibroblasts

Symbol

Name

Log2 fold change

Fold change

Adjusted p-value

Chemokines

CXCL5

Chemokine (C-X-C motif) ligand 5

4.58

16.78

9.18E-07

CXCL6

Chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)

2.50

5.64

1.23E-07

CXCL1

Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

2.06

4.17

1.59E-05

CCL22

Chemokine (C-C motif) ligand 22

1.55

2.93

0.033547076

C5

Complement component 5

0.88

1.85

0.001196477

CCL26

Chemokine (C-C motif) ligand 26

−0.67

−1.59

0.027966918

CCL14

Chemokine (C-C motif) ligand 14

−1.15

−2.22

0.000191918

CCL25

Chemokine (C-C motif) ligand 25

−1.23

−2.35

0.007193543

CCL2

Chemokine (C-C motif) ligand 2

−1.79

−3.46

6.20E-06

Chemokine receptors

CCRL1

Chemokine (C-C motif) receptor-like 1

2.02

4.06

1.37E-05

CCR10

Chemokine (C-C motif) receptor 10

0.98

1.97

0.043411565

CCR8

Chemokine (C-C motif) receptor 8

−0.58

−1.49

0.047496414

CXCR7

Chemokine (C-X-C motif) receptor 7

−2.26

−4.79

1.24E-06

Interleukins

IL8

Interleukin 8

1.47

2.77

0.013242716

IL17D

Interleukin 17D

1.41

2.66

0.000124442

IL1RN

Interleukin 1 receptor antagonist

1.18

2.27

0.007602993

IL1B

Interleukin 1, beta

−1.10

−2.14

0.002340469

IL2

Interleukin 2

−1.19

−2.28

0.034673096

IL32

Interleukin 32

−1.19

−2.28

0.000974257

IL1RAP

Interleukin 1 receptor accessory protein

−1.91

−3.76

8.85E-06

IL33

Interleukin 33

−2.59

−6.02

0.000613327

IL6

Interleukin 6 (interferon, beta 2)

−5.07

−33.59

2.75E-07

Interleukin receptors

IL17RD

Interleukin 17 receptor D

2.24

4.72

0.00026435

IL13RA2

Interleukin 13 receptor, alpha 2

1.84

3.58

3.65E-05

IL15RA

Interleukin 15 receptor, alpha

0.71

1.64

0.015033555

IL21R

Interleukin 21 receptor

−0.86

−1.82

0.004974339

IL20RB

Interleukin 20 receptor beta

−1.29

−2.45

0.000238276

IL1RL1

Interleukin 1 receptor-like 1

−1.99

−3.97

0.002708422

STAT

STAT4

Signal transducer and activator of transcription 4

−1.51

−2.85

1.15E-06

STAT1

Signal transducer and activator of transcription 1

−0.87

−1.83

0.006745

STAT3

Signal transducer and activator of transcription 3 (acute-phase response factor)

−0.87

−1.83

0.021783

Tumor necrosis factor family

TNFAIP8L1

Tumor necrosis factor, alpha-induced protein 8-like 1

3.90

14.93

8.62E-07

TNFRSF25

Tumor necrosis factor receptor superfamily, member 25

1.89

3.71

0.000432746

TNFSF10

Tumor necrosis factor (ligand) superfamily, member 10

1.74

3.34

0.005536998

TNFAIP8L3

Tumor necrosis factor, alpha-induced protein 8-like 3

1.31

2.48

9.01E-05

TNFRSF1B

Tumor necrosis factor receptor superfamily, member 1B

1.20

2.30

0.027881915

TNFRSF21

Tumor necrosis factor receptor superfamily, member 21

0.67

1.59

0.029823686

C1QTNF6

C1q and tumor necrosis factor related protein 6

−0.70

−1.62

0.035969462

TNFRSF10B

Tumor necrosis factor receptor superfamily, member 10b

−0.75

−1.68

0.025993715

C1QTNF3

C1q and tumor necrosis factor related protein 3

−0.81

−1.75

0.013142151

TNFAIP6

Tumor necrosis factor, alpha-induced protein 6

−0.85

−1.80

0.021930255

TNFAIP1

Tumor necrosis factor, alpha-induced protein 1 (endothelial)

−0.87

−1.83

0.002670969

TNFRSF10D

Tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain

−1.14

−2.20

0.003564267

TNFRSF11B

Tumor necrosis factor receptor superfamily, member 11b

−1.59

−3.01

4.04E-05

C1QTNF5|MFRP

Membrane frizzled-related protein, C1q and tumor necrosis factor related protein 5 transcription unit

−2.42

−5.35

5.17E-10

TNFSF4

Tumor necrosis factor (ligand) superfamily, member 4

−2.83

−7.11

4.13E-09

TGFÎ’ pathway

TGFBR3

Transforming growth factor, beta receptor 3

0.94

1.92

0.001259518

TGFBI

Transforming growth factor, beta-induced, 68kDa

−0.66

−1.58

0.014441976

TGFBR1

Transforming growth factor, beta receptor 1

−0.96

−1.91

0.005746781