Table 3 Top five biological functions significantly modulated in backfat adipose tissue when comparing H vs. L animals
Function | Genes | p-Value |
|---|---|---|
Cancer | ACADL, ACAN, ACBD4, ACE2, ACLY, ACTG2, ACVR1C, ADH1A, AFAP1L1, AHSG, ALB, ALDH1A1, ALDOC, ANXA4, AP3M2, APAF1, APOB, AQPEP, ATP5J2, AZGP1, BCHE, BCL10, BMPER, BNIP2, C10orf116, C19orf53, C2orf40, C8A, CA3, CAPN6, CAPZA2, CCBP2, CCL21, CCT6A, CD1E, CD300LG, CENPF, CES1, CHST13, CLCA2, CLEC2D, CLIC5, CLK1, CMPK2, CNN1, COL11A1, COL15A1, COL5A1, COL8A2, COMT, CPXM2, CRABP1, CRABP2, CTCFL, CTNNAL1, CTSF, CXCL1… | 3.36E-07 |
Concentration of lipids | ACACA, ACADL, ACLY, AHSG, ALB, ALDH1A1, APAF1, APOB, APOC3, CD4, CES1, CIDEC, COMT, CTDNEP1, CYP2E1, DHCR24, FASN, FFAR4, GC, GNAT1, HIF1AN, HP, MOGAT2, PHGDH, PLP1, PON1, PON2, PON3, RBP1, RDH16, RGS4, SCD, SNCA, STEAP4, TGFBR2, THEM5, THRSP, UGT8, VAV3 | 1.22E-06 |
Synthesis of lipids | ACACA, ACADL, ACLY, ACSS2, ALB, ALDH1A1, APOB, APOC3, C1QTNF3, CD4, CXCL1, CYP2E1, DHCR24, ESRRG, FASN, G6PD, KDR, KIT, LSS, MOGAT2, NFATC2, PLP1, PMVK, PON1, PON2, PRKG2, RBP1, RDH16, RDH5, SCD, SLC6A6, SNCA, THRSP, UGT8 | 4.85E-06 |
Homeostasis of blood | AHSG, APOC3, APOH, CIDEC, COMT, CYP2E1, ESRRG, MUT, VAV3 | 9.46E-06 |
Fatty acid metabolism | AACS, ACACA, ACADL, ACADSB, ACLY, ACSS2, ALB, APOB, APOC3, APOH, CD4, CXCL1, CYP2E1, EPHX1, FASN, GC, GM2A, KIT, ME1, NFATC2, PHGDH, PLP1, SCD, SLC36A2, SLC38A2, SLCO1A2, SNCA, UGT8 | 1.32E-05 |