Table 4 Top five canonical pathways significantly modulated in backfat adipose tissue when comparing H vs. L animals
Ingenuity canonical pathway | Genes | p-Value |
|---|---|---|
LXR/RXR activation | SCD, APOB, APOH, AHSG, PCYOX1, PON1, ALB, LYZ, APOC3, FASN, ACACA, S100A8, FGA, GC, PON3, TNFRSF11B | 6.19E-10 |
Ethanol Degradation II | ALDH4A1, ADH1A, ALDH1A1, ACSS2, PECR, ADHFE1 | 2.52E-05 |
Noradrenaline and adrenaline degradation | ALDH4A1, ADH1A, ALDH1A1, COMT, PECR, ADHFE1 | 3.58E-05 |
Acute phase response signaling | ALB, HP, RBP7, APOH, AHSG, CRABP2, FGB, FGA, RBP1, FGG, CRABP1, TNFRSF11B | 5.95E-05 |
Superpathway of serine and glycine biosynthesis I | PSPH, PHGDH, SHMT2 | 1.14E-04 |