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Table 2 Detection of single nucleotide variants and error rates in genomic DNA and whole genome amplified DNA

From: Accurate detection of subclonal single nucleotide variants in whole genome amplified and pooled cancer samples using HaloPlex target enrichment

Sample

Somatic SNVsa

Errorb

ALL1_gDNA

227 (13)

0.036

ALL1_wgaDNA

223 (9)

0.020

ALL2_gDNA

305 (5)

0.038

ALL2_wgaDNA

302 (2)

0.031

  1. a Within parenthesis is the number of candidate SNVs that were not classified as somatic in the corresponding gDNA or wgaDNA experiment from the same original sample.
  2. b Average absolute difference from 0.5 for 19 germline SNPs.
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BMC Genomics

ISSN: 1471-2164

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