Figure 3

Dichaete at known target genes. A) Achaete-scute Complex: Dichaete Dam ID binding profiles with 1% and 25% FDR intervals. Dark blue tracks represent FlyLight Enhancers with expression categorised as; small subset of the CNS at stage 16 (st16_CNS_SS), any CNS in germ band extended embryos (GBE) and large subset of the CNS at stage 16 (St16_CNS_LS). Grey bars represent other mapped enhancer elements. Core (red) represents the regions defined as core binding intervals overlapping DamID and ChIP data. The black regions represent gene models and the genome coordinates. B and C) antibody staining revealing l(1)sc expression in wild type (B) and D^r8/Df(3 L)GS1-a (C) stage 16 embryos. P, D and T refer to the protocerebrum, deutocerebrum and tritocerebrum. Red arrowheads indicate loss of l(1)sc expression in the duetocerebrum and tritocerebrum. D) slit tracks as above with FlyLight enhancers identified as expressed in the midline at stage 16.