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Table 1 De novo CNVs in cloned dogs

From: De novo copy number variations in cloned dogs from the same nuclear donor

Clone

Chr

Start (bp)

End (bp)

Length (bp)

Event

Genes*

Validated by

Reported CNV§

Clone-3

15

32,983,895

33,026,044

42,150

CN Gain

-

Q, S

Yes

Clone-3

19

23,000,913

23,338,557

337,644

CN Gain

-

Q, S, B

Yes

Clone-3

32

41,654,990

41,731,424

76,435

CN Gain

-

Q, S

Yes

Clone-3

X

1,401,988

6,598,355

5,196,367

CN Gain

ARSE, ARSH, OBP, GYG2, ARSD, ARSF, MXRA5, PRKX, PRKY, NLGN4T, NLGN4X, HDHD1, STS, PNPLA4, AKL1, TAF9, APOO, SHROOM2

Q, S, B

Yes

Clone-6

2

71,652,481

71,688,546

36,066

CN Loss

ZBTB8A, PCNAP1

Q

No

  1. *Bold text indicates reference genes in canine and regular text indicates reference genes in human.
  2. †Q, genomic qPCR; S, dye-swap array-CGH analysis; B, B-allele profile analysis.
  3. §Overlapped with the previously reported CNVs [1417].