Table 5 Top upstream regulators identified by Ingenuity Pathway Analysis (IPA)
| Â | Top upstream regulators | p-value |
|---|---|---|
A | CD40 ligand (CD154) | 2.25 × 10-24 |
|  | TNF receptor superfamily member 5 (CD40) | 1.05 × 10-22 |
|  | Interleukin 10 (IL-10) | 1.01 × 10-21 |
|  | 5′-inosinic acid (poly rI:rC) | 1.73 × 10-20 |
|  | Lipopolysaccharide (LPS) | 6.21 × 10-20 |
B | Peptidoglycan | 1.79 × 10-13 |
|  | Suppressor of cytokine signaling 1 (SOCS1) | 7.66 × 10-13 |
|  | Tyrphostin AG490 (AG490) | 1.71 × 10-12 |
|  | Interleukin 10 (IL-10) | 3.52 × 10-12 |
|  | Toll-like receptor 2 (TLR2) | 3.55 × 10-12 |