Figure 2

Biological functions significantly affected when comparing the high versus low groups for in vitro production of IL2, IL10, phagocytosis activity and CD4^-/CD8⁺cell counts. Statistical significance of biological functions modulation was calculated via a right-tailed Fisher’s Exact test in Ingenuity Pathway and represented as –log (P value): -log values exceeding 1.30 were significant (FDR q-values < 0.05). For each pathway, the number of affected genes is indicated for each IT in the corresponding coloured box. The numbers of genes that were down-expressed (negative numbers) or up-expressed (positive numbers) in the high group are on the left and right sides of the graph, respectively.