Figure 2

Distribution of MDR1 methylation levels in prostate tissues [benign prostatic hyperplasia (BPH), morphologic normal prostatic tissue (NPT), high-grade prostatic intraepithelial neoplasia (HGPIN), and prostate cancer (PCa)] according with P-gp protein expression categorization [2 ⁺ (expression similar to normal prostate tissue), 1 ⁺ (expression lower than normal prostate tissue), and 0 (no immunoexpression)].