Symbol | Entrez gene name | Fold change | Activation z-score | p-value of overlap | Molecule type |
---|---|---|---|---|---|
Fold change up-regulated | |||||
FN1 | Fibronectin 1 | 74.934 | 2.979 | 8.37E-05 | Enzyme |
CCNA1 | Cyclin A1 | 27.199 | 3.42E-02 | Other | |
IL1B | Interleukin 1, beta | 24.948 | 4.924 | 8.09E-15 | Cytokine |
INHBA | Inhibin, beta A | 21.815 | 1.352 | 2.27E-04 | Growth factor |
SERPINE1 | Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 18.854 | −0.927 | 1.40E-02 | Other |
GDF15 | Growth differentiation factor 15 | 16.924 | 1.999 | 2.63E-02 | Growth factor |
PTHLH | Parathyroid hormone-like hormone | 16.2 | 1.972 | 8.72E-03 | Other |
OSMR | Oncostatin M receptor | 15.366 | 1.982 | 1.83E-02 | Transmembrane receptor |
CXCL10 | Chemokine (C-X-C motif) ligand 10 | 15.171 | 0.911 | 2.31E-02 | Cytokine |
MMP9 | Matrix metallopeptidase 9 (gelatinase B, 92 kDa type IV collagenase) | 14.243 | 0.689 | 1.72E-02 | Peptidase |
IL1R1 | interleukin 1 receptor, type I | 13.972 | 2.603 | 5.76E-03 | Transmembrane receptor |
MMP1 | Matrix metallopeptidase 1 (interstitial collagenase) | 13.875 | 1.188 | 4.01E-03 | Peptidase |
ICAM1 | Intercellular adhesion molecule 1 | 13.681 | 2.961 | 1.36E-03 | Transmembrane receptor |
ITGA5 | Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 13.455 | 2.411 | 1.46E-02 | Other |
SH3KBP1 | SH3-domain kinase binding protein 1 | 12.752 | 4.98E-02 | Other | |
AKT3 | V-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | 11.843 | 4.76E-02 | Kinase | |
LOXL2 | Lysyl oxidase-like 2 | 11.734 | 1.992 | 1.88E-03 | Enzyme |
CEACAM5 | Carcinoembryonic antigen-related cell adhesion molecule 5 | 10.588 | 1.23E-02 | Other | |
SLPI | Secretory leukocyte peptidase inhibitor | 8.53 | −2.433 | 1.06E-02 | Other |
PDZK1IP1 | PDZK1 interacting protein 1 | 8.485 | 1.23E-02 | Other | |
Fold change down-regulated | |||||
CRTAC1 - | Cartilage acidic protein 1 | −72.277 | |||
LPA | Lipoprotein, Lp(a) | −11,623 | 4.98E-02 | Other | |
ETV1 | Ets variant gene 1 | −7,444 | 1.969 | 1.83E-02 | Transcription regulator |
EDNRB | Endothelin receptor type B | −7,25 | 3.38E-02 | G-protein coupled receptor | |
BMP7 | Bone morphogenetic protein 7 | −6,436 | 0.733 | 1.17E-04 | Growth factor |
NREP | Neuronal regeneration related protein | −5,823 | −0.248 | 3.81E-03 | Other |
CFTR | Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | −5,766 | −1.993 | 1.49E-01 | Ion channel |
DCN | Decorin | −5,066 | 0.172 | 6.04E-07 | Other |
RORA | RAR-related orphan receptor alpha | −4,781 | −0.439 | 2.61E-03 | Ligand-dependent nuclear receptor |
LEF1 | Lymphoid enhancer binding factor 1 | −4,441 | −0.306 | 2.01E-02 | Transcription regulator |
BDKRB1 | Bradykinin receptor B1 | −4,1 | −2.000 | 6.89E-04 | G-protein coupled receptor |
GJA1 | Gap junction protein, alpha 1 | −3,94 | −1.480 | 5.54E-04 | Transporter |
FAM3B | Family with sequence similarity 3, member B | −3,9 | 3.20E-08 | Cytokine | |
P2RX7 | Purinergic receptor P2X, ligand-gated ion channel, 7 | −3,885 | 1.15E-02 | Ion channel | |
KAT2B | K(lysine) acetyltransferase 2B | −3,829 | 1.963 | 8.27E-02 | Transcription regulator |
ODC1 | Ornithine decarboxylase, structural 1 | −3,63 | 4.98E-02 | Enzyme | |
EPHX2 | Epoxide hydrolase 2, cytoplasm | −3,469 | 3.42E-02 | Enzyme | |
MAT1A | Methionine adenosyltransferase I, alpha | −3,386 | −0.215 | 1.82E-02 | Enzyme |
CTSL2 | Cathepsin L2 | −3,385 | 4.98E-02 | Peptidase | |
DUSP1 | Dual specificity phosphatase 1 | −3,358 | −1.881 | 6.12E-02 | Phosphatase |
NOV | Nephroblastoma overexpressed | −3,149 | 0.555 | 1.94E-02 | Growth factor |