Figure 2

Phylogenetic analysis of DHA2, ARN and GEX transporters gathered from 31 yeast strains from 25 hemiascomycetous species. A) Radial phylogram showing the amino acid sequence similarity distances between these 355 full-size 14-spanner MFS transporters. B) Circular cladogram showing the tree topology. PROTDIST/NEIGHBOR packages of PHYLIP suite were used in the analysis. Protein and translated ORF names can be consulted in Additional file 2. The name of the S. cerevisiae and C. albicans members is indicated as well as the biochemically characterized Knq1 transporter of K. lactis. The gene and species annotation adopted in this study uses the four letters code described in Table 1. The TCDB protein family classification of S. cerevisiae proteins is also indicated inside parenthesis.