Table 1 List of induced genes in intra-colonic environment compare to spent medium with RT-qPCR confirmation

PFREUD_23410

Permease of glycerol 3 P ABC transporter

1.2 Transport/binding proteins and lipoproteins

4,8

5,0E-08

34,0

1,4E-01

CUST_2220_PI426428742

PFREUD_23760

Xanthine/uracil permease

1.2 Transport/binding proteins and lipoproteins

4,5

6,0E-08

3,7

9,0E-02

CUST_2250_PI426428742

PFREUD_06780

ATP-binding protein of iron compound ABC transporter

1.2.3 Transport/binding of inorganic ions

5,4

7,7E-08

5,1

1,9E-01

CUST_662_PI426428742

PFREUD_16350

Siderophore exporter 2.A.1.38.2

1.2.3 Transport/binding of inorganic ions

4,4

1,3E-07

1,4

2,5E-01

CUST_1559_PI426428742

PFREUD_02570

fepC

Permease component of iron ABC transporter

1.2.3 Transport/binding of inorganic ions

3,5

1,7E-07

3,3

3,1E-01

CUST_254_PI426428742

PFREUD_02700

glpT

Glycerol-3-phosphate transporter

1.2.4 Transport/binding of carbohydrates

3,1

4,1E-07

1,1

2,6E-01

CUST_267_PI426428742

PFREUD_06660

IM protein of ribose/xylose/arabinose/galactoside ABC transporter

1.2.4 Transport/binding of carbohydrates

5,2

1,1E-08

1,2

1,3E-01

CUST_650_PI426428742

PFREUD_12690

ydaO

IM protein of branched-chain amino acids ABC transporter (HAA: undef: Branched-chain amino acids)

1.2.5 Transport/binding of amino-acids

5,7

2,0E-08

3,7

2,0E-01

CUST_1218_PI426428742

PFREUD_03350

cytX

Hydroxymethylpyrimidine transporter CytX

1.2.6 Transport/binding of nucleosides, nucleotides

4,0

1,7E-06

1,4

4,0E-01

CUST_332_PI426428742

PFREUD_15480

ftsQ

Cell division protein FtsQ

1.7 Cell division

4,1

3,0E-07

1,5

3,5E-01

CUST_1474_PI426428742

PFREUD_19110

iolT3

iolT3 (myo-inositol transporter iolT3)

2.1 Metabolism of carbohydrates and related molecules

3,4

7,0E-08

5,9

2,8E-02

CUST_1811_PI426428742

PFREUD_19080

iolB

iolB (Myo-inositol catabolism IolB protein)

2.1.1 Specific carbohydrate metabolic pathway

2,4

3,2E-07

1,9

4,3E-01

CUST_1808_PI426428742

PFREUD_22850

gntP

Gluconate transporter (transmembrane)

2.1.1 Specific carbohydrate metabolic pathway

3,8

3,1E-06

24,1

5,0E-03

CUST_2167_PI426428742

PFREUD_04270

eda, hga, kdgA

2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase

2.1.1 Specific carbohydrate metabolic pathway

2,1

2,6E-05

2,8

2,0E-01

CUST_421_PI426428742

PFREUD_07170

pccB

Propionyl-CoA carboxylase beta chain

2.1.1 Specific carbohydrate metabolic pathway

2,5

8,0E-08

1,1

3,2E-02

CUST_701_PI426428742

PFREUD_09060

dhaG

Glycerol dehydratase reactivation factor DhaG

2.1.1 Specific carbohydrate metabolic pathway

3,8

5,6E-07

4,9

2,5E-02

CUST_877_PI426428742

PFREUD_09130

pduP

CoA-dependent propionaldehyde dehydrogenase PduP

2.1.1 Specific carbohydrate metabolic pathway

5,8

7,7E-08

4,7

4,0E-02

CUST_884_PI426428742

PFREUD_12840

ldh2

L-lactate dehydrogenase

2.1.2 Main glycolytic pathways

3,6

8,3E-07

1,0

1,5E-01

CUST_1233_PI426428742

PFREUD_07770

araD

L-ribulose-5-phosphate 4-epimerase AraD

2.1.2 Main glycolytic pathways

3,3

4,2E-08

4,7

5,9E-02

CUST_759_PI426428742

PFREUD_11340

metH

Methionine synthase (5-methyltetrahydrofolate:L-homocysteine S-methyltransferase)

2.2 Metabolism of amino acids and related molecules

2,1

9,2E-07

5,0

1,6E-01

CUST_1091_PI426428742

PFREUD_12630

cysK

Cysteine synthase (O-acetylserine sulfhydrylase)

2.2 Metabolism of amino acids and related molecules

2,1

7,9E-07

5,3

1,2E-01

CUST_1214_PI426428742

PFREUD_13940

argH

Argininosuccinate lyase (Arginosuccinase)

2.2 Metabolism of amino acids and related molecules

2,3

1,2E-06

2,5

1,3E-01

CUST_1323_PI426428742

PFREUD_02210

bkdB

Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase.

2.2 Metabolism of amino acids and related molecules

2,6

2,9E-06

5,5

4,0E-02

CUST_214_PI426428742

PFREUD_03880

ask

Aspartokinase (Aspartate kinase)

2.2 Metabolism of amino acids and related molecules

3,3

2,5E-07

1,3

1,8E-01

CUST_383_PI426428742

PFREUD_11270

cmk

Cytidylate kinase (CK) (Cytidine monophosphate kinase) (CMP kinase)

2.3 Metabolism of nucleotides and nucleic acids

2,5

9,4E-07

30,0

8,0E-05

CUST_1084_PI426428742

PFREUD_00670

1-acyl-sn-glycerol-3-phosphate acyltransferase

2.4 Metabolism of lipids

4,2

1,1E-08

1,5

3,9E-01

CUST_66_PI426428742

PFREUD_07140

NUDIX hydrolase

2.6 Metabolism of phosphate

3,0

2,1E-07

4,1

2,5E-02

CUST_698_PI426428742

PFREUD_21590

cysW

Sulfate transport system permease protein CysW

2.7 Metabolism of sulfur

4,1

3,6E-07

14,3

2,5E-02

CUST_2047_PI426428742

PFREUD_11100

Single-strand binding protein/Primosomal replication protein

3.1 DNA replication

2,6

1,3E-05

63,5

1,6E-01

CUST_1071_PI426428742

PFREUD_01220

DNA polymerase

3.1 DNA replication

2,3

1,7E-07

3,7

9,0E-02

CUST_124_PI426428742