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Table 4 Transcription of core FeHm-responsive genes in the NTHi isolates 86-028NP and HI1722

From: Comparison of transcription of the Haemophilus influenzae iron/heme modulon genes in vitro and in vivo in the chinchilla middle ear

   Fold Changeb
   86-028NP HI1722
 Locusa  Gene In vitro In vivo c in vitro in vivo d
HI0035   2.25 15.53 1.07 29.37
HI0075 nrdD 2.4 3.81 5.28 21.31
HI0095   9.69 7.11 29.61 22.01
HI0097 hitA 19.92 2.38 66.15 34.66
HI0113 hemR 1.68 2.47 3.02 5.82
HI0153 dcuB 1.96 7.17 1.39 5.57
HI0253 exbB 3.11 -2.44 9.02 37.74
HI0263 hxuB 5.97 5.95 11.91 14.19
HI0362 yfeA 3.14 2.17 19.93 81.46
HI0534 aspA 5.19 6.74 -1.06 36.7
HI0584   1.75 2.52 1.03 10.05
HI0661 hgpB 11.36 3.01 25.6 129.37
HI0691 glpK 1.39 1.22 -1.11 4.26
HI0809 pckA 2.48 1.3 1.51 29.87
HI0994 tbp1 8.73 3.65 15.66 28.3
HI0997m ompU1 12.68 42.36 7.77 30.71
HI1210 mdh 2.11 2.58 1.21 3.5
HI1356 malQ 2.36 10.27 -1.92 10.86
HI1369   8.94 30.26 5.15 30.63
HI1427   3.63 8.8 3.33 7.42
HI0007 fdnH -2.3 1.15 -3.84 1.81
HI0185 adhC -4.48 -1.42 -5.35 -1.42
HI0343 napD -1.38 1.56 1.00 12.4
HI0980 fis -1.05 1.26 -1.18 2.36
HI1069 nrfA -5.08 2.28 -5.06 9.69
HI1078 tcyC -1.92 2.58 -1.01 3.79
HI1094 ccmF -1.51 9.74 -2.01 4.68
HI1384 ftnA -4.27 -7.88 -6.89 -5.41
  1. aGene locus in Rd KW20.
  2. bFold difference in gene expression levels in theFeHm-deplete in vitro sample when normalized to replete condition. Numbers in bold are data points that differ in fold change from that predicted by the core FeHm regulon.
  3. cGeometric mean of 18 samples, normalized to heme-replete in vitro sample.
  4. dGeometric mean of 6 samples, normalized to heme-replete in vitro sample.