Figure 3

Application of QChIPat to TCF7L2 datasets. (A) Visualizations of read counts per bin and genomic locations of various different TCF7L2 binding patterns in MCF7 and PANC1. (B) Four boxplots of log₂(FPKM) gene expression values. Before taking the log₂ of the FPKM values, FPKMs equal to zero were removed and FPKMs between 0 and 1 were changed to 1. I) The boxplot of the MCF7 log₂(FPKM) gene expression values for the genes associated with "MCF7 Only" TCF7L2 binding sites. II) The boxplot of the PANC1 log₂(FPKM) gene expression values for the genes associated with "MCF7 Only" TCF7L2 binding sites. III) The boxplot of the PANC1 log₂(FPKM) gene expression values for the genes associated with "PANC1 Only" TCF7L2 binding sites. IV) The boxplot of the MCF7 log₂(FPKM) gene expression values for the genes associated with "PANC1 Only" TCF7L2 binding sites. (C) IPA analysis of genes associated with TCF7L2 "MCF7 Only" and "PANC1 Only" binding sites respectively.