Figure 1
From: Identification of gene fusions from human lung cancer mass spectrometry data
Workflow for identifying gene fusion and splicing events from MS/MS spectrometry data. A) The external information used for constructing the searchable database B) Five components of the searchable database C) MS/MS data from 40 non-small cell lung cancer(NSCLC) samples and 39 normal lung samples D) Two search engines and strict false discovery rates (FDR) were used to identify the peptides E) More creditable results from the intersection of two search engines and the conservation information F) The distribution of the identified fusion or splicing events among the caner and normal samples.