Dissecting the organ specificity of insecticide resistance candidate genes in Anopheles gambiae: known and novel candidate genes

Table 1 Genes showing the greatest differential expression between resistant and susceptible strains in specific body parts, but which were not identified in whole transcriptome comparisons

AGAP identifier	Description	Tissue	Log₂fold change
AGAP006710	Chymotrypsin-1	Midgut	7.20
AGAP006741	Putative Tight Junction Associated Protein	Abdomen Integument	2.33
AGAP001769	Beat Protein	Abdomen Integument	2.27
AGAP007650	GADD45 (Growth Arrest and DNA Damage Inducible Protein)	Abdomen Integument	2.15
AGAP000717	Monocarboxylate Transporter	Midgut	1.52
AGAP005563	Sugar Transporter	Abdomen Integument	1.91
AGAP009521	Ankyrin Erythrocytic	Abdomen Integument	1.86
AGAP007879	Steroid Dehydrogenase	Midgut	1.74
AGAP013219	Elongase	Abdomen Integument	1.70
AGAP007301	Conserved hypothetical protein	Malpighian Tubules and Midgut	1.61
AGAP001649	Glucosylceramidase	Abdomen Integument	1.11
AGAP006358	TTC27	Abdomen Integument	1.05
AGAP002517	Unknown	Abdomen Integument	0.95
AGAP007691	Serpin 18	Abdomen Integument	0.92(-RC)
AGAP007691	Serpin 18	Abdomen Integument	0.87(-RB)
AGAP005651	Cytoplasmic tRNA 2-thiolation protein	Abdomen Integument	0.80
AGAP004099	Conserved Hypothetical Protein	Abdomen Integument	0.60
AGAP005334	C-Type Lectin	Midgut	-3.62
AGAP003271	Anexin B10B	Midgut	-1.87
AGAP002752	DNAJ Homolog	Remaining Body Parts	-1.10

Splice variants, as predicted by VectorBase, are labelled with variations of -Rx.

ISSN: 1471-2164