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Table 2 Response functions and relation to susceptibility or resistance

From: Comparative transcriptomics of Atlantic Salmo salar, chum Oncorhynchus keta and pink salmon O. gorbuscha during infections with salmon lice Lepeophtheirus salmonis

Function

Response type

 
 

General

Susceptible

Resistant

Systemic or local

 

[A +/or C] + P

[A +/or C] no P

P only

 

Unfolded protein response

Y

  

sys

Acute phase response

Y

  

sys

Prostaglandin production

Y

  

sys

Stress-induced and apoptosis

Y

  

sys/loc

Complement and coagulation

Y

  

sys/loc

Metalloproteinase activity

Y

  

sys/loc

Antiviral suppression

Y

  

sys/loc

Antioxidant activity

Y

  

loc

Antigen presentation suppression

 

Y

 

sys

Reduced hematocrit

 

Y

 

sys

Elevated cortisol

 

Y

 

sys

Iron homeostasis/heme suppression

  

Y

sys

Innate pattern recognition receptor

  

Y

sys

Local inflammation/cytokines

  

Y

loc

  1. Summarized response types of susceptible (Atlantic and chum) and resistant (pink salmon) separated by evidence of a general response (Atlantic and/or chum and pink), a susceptible response (Atlantic and/or chum and not pink) or a resistant response (pink and not Atlantic or chum). Functions are also identified as being present as a systemic response or local response.