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Figure 2 | BMC Genomics

Figure 2

From: Comparison of somatic mutation calling methods in amplicon and whole exome sequence data

Figure 2

Sensitivity of somatic SNV calling methods. The x-axis represents the methods and the y-axis represents sensitivity for (A) amplicon sequencing data and (B) exome sequencing data. C04, C08, C18, and C50 represent mixing concentrations of 8%, 16%, 36%, and 100% samples in amplicon sequencing data, and median allele fractions of 4%, 8%, 18%, and 50% for NA12878 unique heterozygous SNVs in in silico mixture exome sequencing data over the region of interest. For the amplicon sequencing data, columns represent the mean and error bars represent the standard deviation of the triplicate.

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