Figure 9

Cell cycle related gene network. A cell cycle network was constructed using Ingenuity knowledge base tool. Most of the genes in the network were down regulated (green color highlighted) by most of the compounds in the classes of metals and inflammatory mediators, but up regulated by most of the compounds in the classes of antimicrobial, cancer related drugs, pesticides, and PXR mediators. Nf-kB complex is connected with cell cycle genes.