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Table 3 Putative target genes of up-regulated hepatic miRNAs differentially expressed under SNEB

From: Alterations in hepatic miRNA expression during negative energy balance in postpartum dairy cattle

Down-regulated putative targets

Up-regulated putative targets

Symbol

Gene name

Symbol

Gene name

ALDH1A1

aldehyde dehydrogenase 1 family, member A1

AADAT

aminoadipate aminotransferase

BTG1

B-cell translocation gene 1, anti-proliferative

ACP2

Acid phosphatase 2, lysosomal

CCL19

chemokine (C-C motif) ligand 19

ADTRP

Androgen-Dependent TFPI-Regulating Protein

CD14

CD14 molecule

ARG1

Arginase, liver

CIB1

Calcium and integrin binding 1 (calmyrin)

BIN1

Bridging integrator 1

DNAJA1

DnaJ (Hsp40) homolog, subfamily A, member 1

BNIP3L

BCL2/adenovirus E1B 19 kDa interacting protein 3-like

DSG1

desmoglein 1

CMPK1

cytidine monophosphate (UMP-CMP) kinase 1, cytosolic

EPB41L5

Erythrocyte membrane protein band 4.1 like 5

CNN1

Calponin 1, Basic, Smooth Muscle

ERRFI1

ERBB receptor feedback inhibitor 1

CPQ

carboxypeptidase Q

FADS2

Fatty acid desaturase 2

CPT1B

carnitine palmitoyltransferase 1B (muscle)

FOXA3

Forkhead box A3

DENND2D

DENN/MADD domain containing 2D

FXR1

Fragile X mental retardation, autosomal homolog 1

DPYD

dihydropyrimidine dehydrogenase

GKAP1

G kinase anchoring protein 1

HDC

histidine decarboxylase

GNS

glucosamine (N-acetyl)-6-sulfatase

HMGN4

High mobility group nucleosomal binding domain 4

GPBP1

GC-rich promoter binding protein 1

HSF2BP

Heat shock transcription factor 2 binding protein

GPR37

G protein-coupled receptor 37 (endothelin receptor type B-like)

IL1A

Interleukin 1, alpha

HEYL

hairy/enhancer-of-split related with YRPW motif-like

LPCAT3

Lysophosphatidylcholine acyltransferase 3

IP6K2

inositol hexakisphosphate kinase 2

MBL2

Mannose-binding lectin (protein C) 2, soluble (opsonic defect)

KIAA1 191

KIAA1 191

MINA

MYC induced nuclear antigen

MIEN1

Migration and invasion enhancer 1Bottom of Form

NHEJ1

Nonhomologous end-joining factor 1

MIS 12

MIND kinetochore complex component, homolog (S. pombe)

OAT

ornithine aminotransferase (gyrate atrophy)

NR2F1

nuclear receptor subfamily 2, group F, member 1

PDRG1

p53 and DNA-damage regulated 1

PRSS35

protease, serine, 35

POLR3GL

polymerase (RNA) III polypeptide G (32kD)-like

PTPRR

protein tyrosine phosphatase, receptor type, R

RCAN3

RCAN family member 3

RNF 128

ring finger protein 128

REEP5

Receptor accessory protein 5

  1. Putative binding sites were identified in the 3′UTR of differentially expressed hepatic genes under SNEB with the Targetscan algorithm.