Figure 5

Annotation term network created with ClueGo using functional annotation analysis (two-sided hypergeometric test, Benjamini-Hochberg-correction, kappa-score ≥0 . 3). FlybaseIDs of proteins with increased and decreased abundance were searched against GO and KEGG databases. Small circles show involved genes and large circles refer to GO terms. Arrows next to gene names indicate decreased or increased abundance. Colours represent grouping of GO terms whereas size of circle and circle label illustrate the corrected p-value. Abbreviated Drosophila gene names correspond to the following protein names (compare also Tables 1 and 2): Ald – Fructose-Bisphosphate aldolase, ATPsyn-beta – ATP synthase beta, awd – Nucleoside diphosphate kinase, CG10688 – Phosphomannomutase, Cpr50Cb – Cuticle protein, Cpr65Ax1 – Cuticle protein 1c, Edg78E – Cuticle protein 1b, Gapdh2 – GAPDH, l(2)37Cc – Prohibitin, Prm – Paramyosin, serp – Chitin deacetylase 1, verm – Chitin deacetylase 2A, wupA – Troponin.