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Figure 3 | BMC Genomics

Figure 3

From: EgoNet: identification of human disease ego-network modules

Figure 3

Identified ego-networks in the TNBC breast cancer dataset. Module (A) contains major breast cancer genes BRCA1, BRCA2 and TP53. Modules (B) and (C) contain ERBB2 and ESR1 respectively. Examples of other top-scoring modules are shown in (D-F). The area of each node scales with its importance in the classification of the phenotype. Red color indicates differential expression (FDR <0.05 based on a two-tailed t-test with Benjamini & Hochberg FDR adjustment).

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