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Figure 3 | BMC Genomics

Figure 3

From: Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells

Figure 3

Poised and active enhancers. (A) H3K4me1 and H3K27Ac ChIP-seq tags from HMEC at the HSEL were graphed in the heatmap (red: higher density) (left). Mean density of H3K4me1 and H3K27Ac ChIP-seq tags from HMEC at the poised HSEL (top right) and the active HSEL (bottom right) (B) H3K4me1 and H3K27Ac ChIP-seq tags from MDAMB231 at the MSEL were graphed in the heatmap (red: higher density) (left). Mean density of H3K4me1 and H3K27Ac ChIP-seq tags from MDAMB231 at the poised MSEL (top right) and the active MSEL (bottom right) (C) Log fold change of nearby gene expression boxplot for the poised/active HSEL and poised/active MSEL. Student t-test was applied between groups in order to calculate p-values.

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