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Figure 4 | BMC Genomics

Figure 4

From: DNA-encoded nucleosome occupancy is associated with transcription levels in the human malaria parasite Plasmodium falciparum

Figure 4

Nucleosome occupancy in genes and promoter regions of stage-specifically expressed genes. Coverage plots (top row) show average read coverage around the translation start site (-/+500 bp) for all genes with stage-specific expression profiles (as color-indicated in the top left corner) at the four different stages. The number of genes in each group is indicated on the left. At all time points, genes specifically expressed at the schizont and gametocyte (Gameto) stages show a slightly more closed chromatin organization in the promoter region. A relatively large proportion of ring stage-specific genes has a small first exon, resulting in a lower occupancy of the first nucleosome inside the coding region. Heatmap presents normalized read coverage per nucleotide for all genes within each group. Read coverage of the var genes is shown in the bottom row. Read coverage values are expressed on a log 10 scale. Troph: trophozoite stage.

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