Figure 6
From: Whole genome profiling of spontaneous and chemically induced mutations in Toxoplasma gondii
FUDR resistant mutants. (A) The resistance of Toxoplasma strains to varying concentrations of FUDR. Survival was determined by plaque formation relative to an untreated control. Error bars represent SD from 6 independent experiments. Both strains were initially selected for survival in the presence of 20 μM FUDR. (B) Proposed etiological mutation in UPRT identified in mutant EMS7.5. Genbank accession numbers for HsUPRT and DmUPRT are NP_659489 and CG5537, respectively.