Figure 2

Interactome of PTPRJ indicates that the inactivation of PTPRJ may affect cellular networks and that these networks are not only altered by inactivation of PTPRJ . PTPRJ gene network showing A) all the known genes that interact with PTPRJ and B) only those genes that were also found to be inactivated in NHL cases. Two levels of interaction were used to filter the interactions. Interestingly, we found that the gene PTPN11, which was also found inactivated in NHL cases, shares some target genes with PTPRJ; moreover, B2M has an indirect interaction with PTPRJ (red arrows).