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Table 3 KEGG pathways enriched for targets of the 16 down-regulated miRNAs in the backfat tissues of castrated pigs

From: A comprehensive microRNA expression profile of the backfat tissue from castrated and intact full-sib pair male pigs

Signaling pathway term

Count

P-value

Benjamini

Neurotrophin signaling pathway

47

9.70 E-11

1.70 E-08

Focal adhesion

55

9.90 E-07

5.90 E-05

Regulation of actin cytoskeleton

56

4.10 E-06

1.50 E-04

Insulin signaling pathway

40

5.10 E-06

1.50 E-04

Wnt signaling pathway

41

3.70 E-05

6.70 E-04

Adherens junction

25

9.10 E-05

1.40 E-03

Long-term potentiation

23

9.60 E-05

1.30 E-03

ErbB signaling pathway

27

1.00 E-04

1.30 E-03

MAPK signaling pathway

60

2.00 E-04

2.00 E-03

Ubiquitin mediated proteolysis

34

1.10 E-03

9.60 E-03

Chemokine signaling pathway

43

1.20 E-03

9.50 E-03

Endocytosis

41

2.90 E-03

2.10 E-02

Aldosterone-regulated sodium reabsorption

14

3.10 E-03

2.20 E-02

Hedgehog signaling pathway

17

3.60 E-03

2.50 E-02

T cell receptor signaling pathway

26

7.40 E-03

4.70 E-02

Type II diabetes mellitus

14

1.10 E-02

6.30 E-02

Phosphatidylinositol signaling system

19

1.30 E-02

7.00 E-02

Vascular smooth muscle contraction

25

2.20 E-02

1.10 E-01

Fc gamma R-mediated phagocytosis

22

2.20 E-02

1.10 E-01

TGF-beta signaling pathway

20

3.20 E-02

1.40 E-01

Inositol phosphate metabolism

14

3.40 E-02

1.40 E-01

mTOR signaling pathway

13

5.50 E-02

2.10 E-01

Leukocyte transendothelial migration

24

6.40 E-02

2.30 E-01

Cell cycle

25

6.90 E-02

2.40 E-01

Gap junction

19

7.00 E-02

2.40 E-01

GnRH signaling pathway

20

9.10 E-02

2.90 E-01

p53 signaling pathway

15

9.10 E-02

2.90 E-01