Table 2 GO terms for differentially expressed genes

Glycoprotein

A_70_P042906

2.22

1.00

AQP1

Aquaporin 1 (Colton blood group)

CUST_5666_PI375351158

−2.02

−1.16

AQP4

Aquaporin 4

[10]

A_70_P041077

2.09

1.39

PTGER3

Prostaglandin E receptor 3 (subtype EP3)

A_70_P030356

1.48

−2.06

SLC11A1

Solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1

A_70_P051037

−2.09

2.85

SLC2A5

Solute carrier family 2 (facilitated glucose/fructose transporter), member 5

[10]

A_70_P036386

−1.29

−2.01

UCHL1*

Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

Extracellular region

CUST_2502_PI375351158

2.26

2.76

BMPER

BMP binding endothelial regulator

A_70_P006426

4.26

1.06

FGL1

Fibrinogen-like 1

A_70_P069571

2.05

1.93

FIBIN

Fin bud initiation factor homolog (zebrafish)

A_70_P038041

1.95

−3.63

HP

Haptoglobin

[10]

CUST_3439_PI375351158

2.70

1.38

PIGR

Polymeric immunoglobulin receptor

A_70_P035871

1.03

−3.29

SERPINE1*

Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

A_70_P039451

−1.57

−2.28

SFN

Stratifin

A_70_P050922

2.19

−1.06

VEGFA*

Vascular endothelial growth factor A

Disulfide bond

CUST_598_PI375351158

2.28

1.33

FABP5

Fatty acid binding protein 5 (psoriasis-associated)

A_70_P070736

−3.83

−1.06

TXNRD1

Thioredoxin reductase 1

Cell cycle

A_70_P058586

−2.85

−1.55

PSMA7*

Proteasome (prosome, macropain) subunit, alpha type, 7

A_70_P057841

−1.61

−2.51

BRCA2

Breast cancer 2, early onset

A_70_P053686

1.11

−2.01

CCNDBP1

Cyclin D-type binding-protein 1

A_70_P060136

−1.48

−2.04

CGREF1

Cell growth regulator with EF-hand domain 1

A_70_P027076

−2.79

−1.28

EID1

EP300 interacting inhibitor of differentiation 1

A_70_P007666

−2.87

−1.61

KIF2C

Kinesin family member 2C

A_70_P011891

−2.34

−1.29

MND1

Meiotic nuclear divisions 1 homolog (S. cerevisiae)

A_70_P009551

−2.13

−1.07

NCAPG

Non-SMC condensin I complex, subunit G

A_70_P037556

−2.12

1.01

NDC80

NDC80 homolog, kinetochore complex component (S. cerevisiae)

A_70_P034256

−2.20

1.05

TFDP2

Transcription factor Dp-2 (E2F dimerization partner 2)

A_70_P061801

−2.01

−1.39

UBE2C

Ubiquitin-conjugating enzyme E2C

Condensed chromosome

CUST_7895_PI375351158

−2.79

−1.15

HMGB1

High-mobility group box 1

A_70_P003816

−2.20

−1.67

TEX12

Testis expressed 12

Alternative splicing

A_70_P059171

−2.57

−2.17

CLTA

Clathrin, light chain (Lca)

A_70_P033441

1.13

2.27

MEST

Mesoderm specific transcript homolog (mouse)

A_70_P039536

−2.86

−1.34

MX1

Myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

A_70_P060791

2.25

1.38

PEG3

Paternally expressed 3

A_70_P015446

−1.52

−2.13

UNC50

Unc-50 homolog (C. elegans)

Chromosome

A_70_P065046

−2.68

−1.32

JRKL

Jerky homolog-like (mouse)

A_70_P040916

−2.62

−1.67

ORC1L

Origin recognition complex, subunit 1-like (yeast)

CUST_12205_PI375351158

−2.04

−1.20

TOP2A

Topoisomerase (DNA) II alpha 170 kDa

[33]

Extracellular matrix

A_70_P021711

−2.19

−1.69

COL1A1

Collagen, type I, alpha 1

[10, 16]

CUST_11292_PI375351158

2.40

1.12

CRISPLD2

Cysteine-rich secretory protein LCCL domain containing 2

A_70_P007356

2.20

1.26

DCN

Decorin

[10, 16]

CUST_7449_PI375351158

1.46

−2.05

DPT

Dermatopontin

A_70_P032476

2.45

−1.35

MFAP5

Microfibrillar associated protein 5

[10]

A_70_P058626

2.27

1.13

VWF

Von Willebrand factor

Signal peptide

A_70_P064081

2.44

−2.18

CA4

Carbonic anhydrase IV

A_70_P061221

1.20

−2.43

P4HA1

Prolyl 4-hydroxylase, alpha polypeptide I

[10, 11]

A_70_P040831

−2.09

−1.07

SELL

Selectin L

Tumor suppressor

A_70_P035971

2.05

−1.75

VWA5A

Von Willebrand factor A domain containing 5A

A_70_P026737

3.11

−1.41

WT1

Wilms tumor 1

A_70_P061691

1.26

2.26

HPGD

Hydroxyprostaglandin dehydrogenase 15-(NAD)

Cytoplasm

A_70_P016337

−1.78

−2.72

HMMR

Hyaluronan-mediated motility receptor (RHAMM)

CUST_12176_PI375351158

−1.04

−2.92

ACTG2

Actin, gamma 2, smooth muscle, enteric

A_70_P019656

1.01

3.59

ADH1A

Alcohol dehydrogenase 1A (class I), alpha polypeptide

A_70_P045301

3.70

2.33

BBOX1*

Butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1

A_70_P069971

−2.09

−1.73

CDC42EP5

CDC42 effector protein (Rho GTPase binding) 5

CUST_5823_PI375351158

1.12

2.07

NIN

Ninein (GSK3B interacting protein)

A_70_P018021

−3.25

−1.15

PAIP2

Poly(A) binding protein interacting protein 2

A_70_P054126

−2.16

−1.11

PHAX

Phosphorylated adaptor for RNA export

A_70_P044246

1.26

−2.14

RRAGD

Ras-related GTP binding D

A_70_P055106

2.05

1.07

SORBS2

Sorbin and SH3 domain containing 2

A_70_P025726

−2.39

−1.60

STMN2

Stathmin-like 2

A_70_P060991

−2.80

1.21

CA3

Carbonic anhydrase III, muscle specific

Fatty acid metabolism

CUST_8730_PI375351158

1.06

−2.05

ACSL4

Acyl-CoA synthetase long-chain family member 4

A_70_P039986

−1.27

2.39

SLC27A2

Solute carrier family 27 (fatty acid transporter), member 2

Phosphatidic acid metabolic process

A_70_P039726

−2.50

−1.10

AGPAT1

1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)

A_70_P025121

−3.34

−1.30

PLA2G2A

Phospholipase A2, group IIA (platelets, synovial fluid)

Protein dimerization activity

CUST_206_PI396851701

2.04

−2.28

FOS

v-fos FBJ murine osteosarcoma viral oncogene homolog

[10, 11, 33]

CUST_10535_PI375351158

−2.41

−2.41

NFE2L1

Nuclear factor (erythroid-derived 2)-like 1

Zinc finger, C2H2-type

CUST_13307_PI375351158

−2.34

−1.26

ATMIN

ATM interactor

A_70_P036056

−2.65

−1.71

KLF6

Kruppel-like factor 6

A_70_P065371

−2.27

−1.13

ZCCHC6

Zinc finger, CCHC domain containing 6

A_70_P014286

1.33

2.01

ZNF45

Zinc finger protein 45

Cytoplasmic membrane-bounded vesicle

A_70_P062831

−3.71

−1.48

EHD3

EH-domain containing 3

A_70_P044621

2.27

−1.04

MALL

Mal, T-cell differentiation protein-like

Metal ion transport

A_70_P030126

−2.36

1.24

CP*

Ceruloplasmin (ferroxidase)

[10, 16]

CUST_12632_PI375351158

2.28

1.50

KCTD12

Potassium channel tetramerisation domain containing 12

A_70_P027206

2.15

2.10

SLC30A1

Solute carrier family 30 (zinc transporter), member 1

[10, 11]

A_70_P050456

−2.65

−1.58

SLC38A10

Solute carrier family 38, member 10

Antimicrobial

CUST_139_PI396851701

15.26

−1.74

CATHL1

Cathelicidin 1

CUST_3993_PI375351158

5.96

−1.25

S100A8

S100 calcium binding protein A8

[10]

Apoptosis

CUST_260_PI396851701

−2.04

−1.55

CARD6

Caspase recruitment domain family, member 6

A_70_P022526

−2.29

−1.16

OPA1

Optic atrophy 1 (autosomal dominant)

A_70_P049526

−1.12

−2.70

PERP

PERP, TP53 apoptosis effector

A_70_P069836

−3.14

−1.31

RNF130

Ring finger protein 130

A_70_P067091

−2.90

−1.55

UBE2Z

Ubiquitin-conjugating enzyme E2Z

Immunoglobulin-like fold

A_70_P036361

2.06

2.09

CD1E

CD1e molecule

CUST_9656_PI375351158

−2.03

1.11

FGFR2

Fibroblast growth factor receptor 2

CUST_12141_PI375351158

2.64

−1.00

IGK

Ig kappa chain

A_70_P016986

−2.23

1.16

TRD@

T cell receptor delta locus

[11]

Secreted

A_70_P048761

1.34

−2.27

SPINK5

Serine peptidase inhibitor, Kazal type 5

CUST_9580_PI375351158

1.13

−2.49

MMRN1

Multimerin 1

CUST_10101_PI375351158

−1.07

−2.53

NPNT

Nephronectin

A_70_P034356

2.88

1.19

SEMA3G

Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G

A_70_P063891

2.38

−1.22

PCOLCE2

Procollagen C-endopeptidase enhancer 2

GTP binding

A_70_P019676

4.33

1.16

ACSM1

Acyl-CoA synthetase medium-chain family member 1

[10]

A_70_P046951

−2.24

−1.02

ARL4C

ADP-ribosylation factor-like 4C

A_70_P008796

−2.06

1.15

DOCK11

Dedicator of cytokinesis 11

A_70_P000126

−3.63

−1.82

GBP4

Guanylate binding protein 4

Disulfide bond

A_70_P018376

2.56

−1.08

FAP

Fibroblast activation protein, alpha

A_70_P041321

−2.15

−2.57

IGHA2

Immunoglobulin heavy constant alpha 2 (A2m marker)

Structural molecule activity

A_70_P028306

−2.03

−1.05

LMNB1

Lamin B1

CUST_13373_PI375351158

−2.15

−1.29

LOC531679

Ribosomal protein 17-like; similar to 60S ribosomal Protein L17 (L23); similar to ribosomal protein L17; similar to Rpl17 protein; similar to mCG3798

CUST_7057_PI375351158

−2.33

−1.07

LOC789587

Similar to Ribosomal_L22 domain containing protein RGD1359290

A_70_P031441

−2.43

−1.79

VCL

Vinculin

[11]

Positive regulation of inflammatory response

A_70_P058551

8.25

−1.12

FABP4

Fatty acid binding protein 4, adipocyte

CUST_9779_PI375351158

−1.40

−2.38

IDO1

Indoleamine 2,3-dioxygenase 1

Other

CUST_13467_PI375351158

1.29

−2.14

FBP2

Fructose-1,6-bisphosphatase 2

A_70_P055306

2.77

1.50

SLC43A1

Solute carrier family 43, member 1

A_70_P049406

−1.99

−2.32

EIF5

Eukaryotic translation initiation factor 5

[11]

A_70_P070931

−2.87

−1.18

NUDT19

Nudix (nucleoside diphosphate linked moiety X)-type motif 19

A_70_P036101

1.22

−3.18

NOP10

NOP10 ribonucleoprotein homolog (yeast)

[11]

A_70_P011091

−2.74

−2.01

PFDN2*

Prefoldin subunit 2

A_70_P039656

17.20

−1.52

BAC5

5 kDa bactinecin precursor

A_70_P061341

−1.03

−2.94

C11ORF10

Chromosome 11 open reading frame 10

A_70_P061266

2.36

1.03

C5ORF43

Chromosome 5 open reading frame 43

A_70_P051377

14.99

−1.48

CATHL1B

Procyclic dodecapeptide

A_70_P015101

−2.70

−1.03

CCDC82

Coiled-coil domain containing 82

A_70_P012541

−1.02

−2.36

CNN1

Calponin 1, basic, smooth muscle

A_70_P002841

2.03

1.48

EPAS

Endothelial PAS domain protein 1

A_70_P008841

−2.18

−1.23

EPSTI1

Epithelial stromal interaction 1 (breast)

A_70_P060756

−2.12

1.08

FAM190B

KIAA1128

A_70_P062951

2.05

1.12

FNDC3B

Fibronectin type III domain containing 3B

[33]

A_70_P051181

2.76

1.28

HSD11K

NAD-dependent 11-beta-hydroxysteroid dehydrogenase

CUST_46_PI396851701

−2.06

−2.15

IGHA

Immunoglobulin heavy constant alpha

A_70_P024671

2.46

1.31

INHBB

Inhibin, beta B

A_70_P033656

−2.34

−1.77

ISG12(A)

ISG12(a) protein-like

A_70_P012537

−2.19

−3.58

LGALS15

Galectin 15

CUST_3620_PI375351158

−1.58

−2.22

LGALS16

Beta-galactoside-binding lectin

A_70_P020131

−1.10

−3.84

LGALS9C

Lectin, galactoside-binding, soluble, 9C

CUST_6089_PI375351158

−2.02

−1.71

LOC100140018

Similar to cytochrome P450, family 2, subfamily J

A_70_P016801

−2.20

−1.48

LOC443321

Lysozyme 2a precursor

A_70_P026671

−1.91

−2.05

LOC524810

IgM

A_70_P023026

3.09

1.74

LOC615697

Similar to cytochrome P450

A_70_P039266

−2.03

−1.83

LOC654331

Pancreatitis-associated protein I

[10]

A_70_P039271

−3.94

−7.40

MCP-4

Mast cell proteinase-4

CUST_11558_PI375351158

2.00

2.23

MGC140754

Hypothetical LOC508613

CUST_9725_PI375351158

−2.26

−3.77

PLAC8

Placenta-specific 8

CUST_10114_PI375351158

2.56

1.15

RN18S1

18S ribosomal RNA

A_70_P030132

−2.40

−1.71

RTP4

Receptor (chemosensory) transporter protein 4

[34]

A_70_P030426

10.95

1.39

SC5

Cathelin-related prepropeptide