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Figure 9 | BMC Genomics

Figure 9

From: 8p23 beta-defensin copy number determination by single-locus pseudogene-based paralog ratio tests risk bias due to low-frequency sequence variations

Figure 9

PRT4 primer design and locus specificity. Partial sequences of HSPDP3 paralogs on different chromosomes are shown. The primers were designed to amplify loci only on chromosome 8 (target) and chromosome 4 (reference). Gray: amplified loci; green: primer binding site with perfect match; yellow: primer binding site with mismatches; purple: mismatch; red: deletion which generates the length difference of PCR products; blue: paralogous sequence variation rs187261177.

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