Figure 2

Steps in sample use case 1. A) A reconstruction of the pathway published in the manuscript by the TCGA network [16]. In the original figure, alteration frequencies are shown for three subgroups of cases, but we merge these into one in this version. B) Dialog to retrieve alteration data from the cBioPortal. C) Paths from ERBB2 to KRAS in Pathway Commons, overlayed with alteration data of endometrial cancer from the cBioPortal. This diagram is part of the result that was automatically generated by ChiBE using the menu item "Query | Pathway Commons (Level 3) | Paths From To". D) Oncoprint of the related genes, generated by the cBioPortal. Genes from C are shown above the black line, and altered genes from A are shown under the black line.