Figure 8
From: Combinatorial epigenetic patterns as quantitative predictors of chromatin biology
Epigenetic reprogramming of the pluripotency network. Association of histone modification changes and NMF codes with genes involved in pluripotency. Myc/Max, Nanog, Oct4, Sox2 are shorthand for experimental targets of these TFs in human embryonic stem cells. PluriNet are genes involved in the protein-protein interactions networks discovered in pluripotent cells. Stem are genes up-regulated in embryonic stem cells shared between mouse and human. The five marks or codes most significantly (p-value) associated with each group of genes are shown.