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Table 2 Statistical association of epigenetic remodelling patterns and molecular pathways during myoblast differentiation

From: Combinatorial epigenetic patterns as quantitative predictors of chromatin biology

Code

Pathway identifier in MSigDB

p-value (FDR)

code 2

REACTOME_GPCR_LIGAND_BINDING

1.25E-48

code 2

REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS

5.80E-39

code 2

KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

1.57E-34

code 2

REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

2.00E-32

code 2

KEGG_OLFACTORY_TRANSDUCTION

2.09E-17

code 2

KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION

4.39E-12

code 3

REACTOME_GENERIC_TRANSCRIPTION_PATHWAY

1.18E-11

code 3

REACTOME_TRANSCRIPTION

3.38E-08

code 3

REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED...

1.41E-06

code 3

REACTOME_METABOLISM_OF_PROTEINS

3.68E-06

code 3

KEGG_SPLICEOSOME

3.68E-06

code 3

REACTOME_MUSCLE_CONTRACTION

6.62E-06

code 4

REACTOME_CELL_CYCLE_MITOTIC

1.88E-07

code 5

REACTOME_CELL_CYCLE

2.28E-68

code 5

REACTOME_CELL_CYCLE_MITOTIC

4.19E-48

code 5

REACTOME_TRANSCRIPTION

7.90E-35

code 5

REACTOME_MITOTIC_M_M_G1_PHASES

1.10E-31

code 5

REACTOME_DEPOSITION_OF_NEW_CENPA_...

1.69E-28

code 5

KEGG_SPLICEOSOME

2.32E-27

code 6

REACTOME_CELL_CYCLE

2.15E-06

code 8

REACTOME_GENERIC_TRANSCRIPTION_PATHWAY

1.64E-09

  1. For each of the "gain-loss" basis patterns only the most significant (FDR-corrected) terms are shown for each code. Pathway gene annotations and identifiers are from MSigDB, but are originally sourced from KEGG and Reactome. Codes that did not have any significant terms at the 1E-6 level were omitted.