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Figure 1 | BMC Genomics

Figure 1

From: Chromothripsis-like patterns are recurring but heterogeneously distributed features in a survey of 22,347 cancer genome screens

Figure 1

Detection of chromothripsis-like patterns from genomic arrays. (A) Schematic description of the detection procedure. Raw array data of 402 GEO series are first collected and re-analyzed, then annotated and stored in arrayMap database. For high quality arrays, a scan-statistic based algorithm was employed to identify CTLP cases. (B) The ROC curve of the training set and selected thresholds. Two predictors were tested, copy number status change times and the likelihood ratio. Both predictors were integrated into the combined threshold.

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