Table 2 Frequency of chromothripsis-like patterns among cancer types
Chromothripsis-like cases | ||||||
|---|---|---|---|---|---|---|
Cancer type | Oligo > 200 K | Oligo ≤ 200 K | BAC or cDNA | Total | Input cases | Frequency (95% confidence interval) |
Soft tissue tumors: lipoid | 49 | 12 | 0 | 61 | 114 | 53.5% (44%–62.8%) |
Soft tissue tumors: fibroid tumors | 14 | 0 | 0 | 14 | 59 | 23.7% (14%–36.9%) |
Soft tissue tumors: sarcomas, other | 9 | 0 | 2 | 11 | 48 | 22.9% (12.5%–37.7%) |
Carcinomas: breast ca. | 247 | 99 | 58 | 404 | 3652 | 11.1% (10.1%–12.1%) |
Carcinomas: esophagus ca. | 13 | 0 | 0 | 13 | 135 | 9.6% (5.4%–16.2%) |
Carcinomas: bronchoalveolar, NSCLC | 78 | 29 | 2 | 109 | 1164 | 9.4% (7.8%–11.2%) |
Soft tissue tumors: bone tumors | 7 | 3 | 0 | 10 | 123 | 8.1% (4.2%–14.8%) |
Carcinomas: bronchoalveolar, SCLC | 3 | 3 | 0 | 6 | 90 | 6.7% (2.7%–14.5%) |
Carcinomas: prostate adenoca. | 1 | 40 | 0 | 41 | 653 | 6.3% (4.6%–8.5%) |
CNS: CNS PNET | 4 | 0 | 0 | 4 | 65 | 6.2% (2%–15.8%) |
Carcinomas: melanocytic neoplasias | 31 | 1 | 6 | 38 | 621 | 6.1% (4.4%–8.4%) |
Soft tissue tumors: myoepithelial | 3 | 0 | 2 | 5 | 85 | 5.9% (2.2%–13.8%) |
Carcinomas: ovarian ca. | 31 | 5 | 1 | 37 | 801 | 4.6% (3.3%–6.4%) |
Carcinomas: gastric ca. | 1 | 5 | 1 | 7 | 160 | 4.4% (1.9%–9.2%) |
CNS: gliomas | 14 | 13 | 0 | 27 | 669 | 4% (2.7%–5.9%) |
Soft tissue tumors: stromal tumors | 5 | 1 | 0 | 6 | 151 | 4% (1.6%–8.8%) |
CNS: medulloblastomas | 13 | 4 | 0 | 17 | 430 | 4% (2.4%–6.4%) |