Figure 1

Quantile-quantile plot of human homologues of significant mouse genes for hippocampus size. For genes with a significant influence on hippocampus weight in mice (≤0.05) the significance of their influence on human hippocampus volume was plotted against a normal distribution of p-values. Although there are outliers, most of the points lie close to the y = x line, indicating there is no difference between what is seen in the data and what would be expected by chance. This is reinforced by the non-significant lambda value close to 1, which indicates no inflation of significance values.