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Table 1 Empirical Type I error rate (empirical power) of IUTA_SKK at nominal Type I error rate 0.05 for various levels of read coverage for a selection of genes

From: IUTA: a tool for effectively detecting differential isoform usage from RNA-Seq data

Gene

No. of isoforms

Read coverage

10

30

50

70

90

110

Zfp407

2

0.06 (0.99)

0.08 (1.00)

0.08 (1.00)

0.08 (1.00)

0.08 (1.00)

0.07 (1.00)

Loxl2

3

0.07 (1.00)

0.07 (1.00)

0.10 (0.99)

0.09 (1.00)

0.11 (0.99)

0.11 (0.99)

Bptf

5

0.30 (0.96)

0.29 (0.96)

0.27 (0.96)

0.27 (0.95)

0.25 (0.95)

0.23 (0.96)

Pde4dip

7

0.04 (0.92)

0.04 (0.94)

0.07 (0.95)

0.04 (0.93)

0.06 (0.96)

0.07 (0.96)

Dido1

8

0.11 (0.87)

0.10 (0.89)

0.10 (0.90)

0.11 (0.88)

0.11 (0.87)

0.10 (0.89)

Ifi203

8

0.09 (0.77)

0.10 (0.76)

0.08 (0.77)

0.09 (0.70)

0.10 (0.76)

0.09 (0.74)

Stab2

8

0.08 (0.35)

0.07 (0.43)

0.06 (0.45)

0.07 (0.44)

0.07 (0.51)

0.08 (0.44)