Figure 1
From: MicroRNA-34c is associated with emphysema severity and modulates SERPINE1 expression
Correlation plots of the five candidate miRNAs and emphysema status. The expression of the differentially expressed microRNAs for the 29 patients and their emphysema status (KCO% predicted corrected for hemoglobin) is shown. The correlation of miR34c expression determined by microarrays in lung tissues to its consequent KCO measurements were not significant (p > 0.05). However this miRNA was chosen for cell line studies as it portrayed siginificant difference in gene expression between patient groups i.e. moderate vs mild emphysema lungs. MiRNA levels ofthe 29 samples are drawn on the X-axis, KCO% predicted on the left Y-axis and microRNA expression on the right Y-axis. * indicates a correlation of significance p < 0.05 and ** indicates a correlation of significance p < 0.01.