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Table 1 GO analysis for the top 2000 mouse and rat dendritic expressed genes

From: Divergence of RNA localization between rat and mouse neurons reveals the potential for rapid brain evolution

(A) GO analysis for the top 2000 mouse dendritic expressed genes

Category

GO_Term

GO_Description

FDR

Biological process

GO:0009987

Cellular process

4.5E-26

 

GO:0044237

Cellular metabolic process

4.8E-10

 

GO:0006412

Translation

1.1E-06

 

GO:0051179

Localization

5.3E-06

 

GO:0006091

Generation of precursor metabolites and energy

1.9E-05

 

GO:0007399

Nervous system development

1.7E-04

 

GO:0022900

Electron transport chain

8.5E-04

 

GO:0006810

Transport

1.1E-03

 

GO:0019538

Protein metabolic process

2.1E-02

 

GO:0006119

Oxidative phosphorylation

3.7E-02

 

GO:0022008

Neurogenesis

4.0E-02

Cellular component

GO:0005840

Ribosome

5.3E-09

 

GO:0030529

Ribonucleoprotein complex

1.8E-07

 

GO:0043227

Membrane-bounded organelle

1.8E-07

 

GO:0043228

Non-membrane-bounded organelle

2.5E-07

 

GO:0043232

Intracellular non-membrane-bounded organelle

2.5E-07

 

GO:0070469

Respiratory chain

7.7E-07

 

GO:0031966

Mitochondrial membrane

8.3E-07

 

GO:0005740

Mitochondrial envelope

4.4E-06

 

GO:0019866

Organelle inner membrane

6.2E-06

 

GO:0005743

Mitochondrial inner membrane

6.3E-06

 

GO:0031090

Organelle membrane

2.6E-05

 

GO:0031967

Organelle envelope

2.6E-05

 

GO:0044429

Mitochondrial part

3.1E-05

 

GO:0005856

Cytoskeleton

4.3E-04

Molecular function

GO:0005198

Structural molecule activity

1.5E-07

 

GO:0005515

Protein binding

3.8E-06

 

GO:0015077

Monovalent inorganic cation transmembrane transporter activity

5.2E-02

 

GO:0003954

NADH dehydrogenase activity

7.4E-02

 

GO:0008137

NADH dehydrogenase (ubiquinone) activity

7.4E-02

 

GO:0050136

NADH dehydrogenase (quinone) activity

7.4E-02

 

GO:0015078

Hydrogen ion transmembrane transporter activity

7.8E-02

(B) GO analysis for the top 2000 rat dendritic expressed genes

Category

GO_Term

GO_Description

FDR

Biological process

GO:0009987

Cellular process

5.84E-31

 

GO:0006414

Translational elongation

1.13E-04

 

GO:0007399

Nervous system development

1.76E-04

 

GO:0034621

Cellular macromolecular complex subunit organization

2.50E-04

 

GO:0022008

Neurogenesis

1.22E-03

 

GO:0034622

Cellular macromolecular complex assembly

3.06E-03

 

GO:0051179

Localization

1.12E-08

 

GO:0006810

Transport

2.09E-07

 

GO:0001568

Blood vessel development

3.56E-03

 

GO:0048514

Blood vessel morphogenesis

6.73E-03

Cellular component

GO:0043234

Protein complex

4.38E-06

 

GO:0031090

Organelle membrane

1.59E-05

 

GO:0043005

Neuron projection

8.96E-05

 

GO:0005740

Mitochondrial envelope

1.19E-04

 

GO:0031966

Mitochondrial membrane

1.28E-04

 

GO:0044445

Cytosolic part

1.83E-04

 

GO:0022626

Cytosolic ribosome

4.25E-04

 

GO:0022627

Cytosolic small ribosomal subunit

8.11E-04

 

GO:0044429

Mitochondrial part

2.95E-03

 

GO:0015935

Small ribosomal subunit

5.33E-03

 

GO:0019866

Organelle inner membrane

1.68E-02

 

GO:0070469

Respiratory chain

2.09E-02

 

GO:0005743

Mitochondrial inner membrane

3.53E-02

 

GO:0043228

Non-membrane-bounded organelle

4.89E-02

 

GO:0043232

Intracellular non-membrane-bounded organelle

4.89E-02

Molecular function

GO:0005515

Protein binding

9.71E-25

 

GO:0005516

Calmodulin binding

2.09E-02

 

GO:0015078

Hydrogen ion transmembrane transporter activity

3.35E-02

 

GO:0015077

Monovalent inorganic cation transmembrane transporter activity

7.52E-02

  1. GO analysis for the top2000 ranked dendritic genes in mouse (A) and rat (B) with FDR < 0.1 used as threshold value.
  2. GO categories in "bold" correspond to categories found commonly in rat and mouse.