Divergence of RNA localization between rat and mouse neurons reveals the potential for rapid brain evolution

Francis, Chantal; Natarajan, Shreedhar; Lee, Miler T; Khaladkar, Mugdha; Buckley, Peter T; Sul, Jai-Yoon; Eberwine, James; Kim, Junhyong

doi:10.1186/1471-2164-15-883

BMC Genomics

Table 2 Synaptic plasticity genes show divergent level of expression in rats and mice dendrites

From: Divergence of RNA localization between rat and mouse neurons reveals the potential for rapid brain evolution

Family	Class	Synaptic function	Gene symbol	Rat	Balb/c	C57BL/6
Channel	Voltage-gated	–	*Trpm1*	+	-	-
Channel	Voltage-gated	ARGs, LTP	*Cnga2* ^ab	+	-	-
Channel	Voltage-gated	–	*Cacna1g*	+	-	-
Channel	Ligand-gated	–	*Chrna1*	+	+	+
Channel	Voltage-gated	LTP	*Hcn1* ^b	+	+	+
Channel	Voltage-gated	–	*Kcnn2*	-	+	+
Gprotein	Gprotein	–	*Gng11*	+	+	+
Receptor	GPCR_A	LTP	*Htr1f* ^b	+	-	-
Receptor	GPCR_A	–	*Ghsr*	+	-	-
Receptor	GPCR_A	–	*P2ry6*	+	-	-
Receptor	GPCR	–	*Gpr108*	+	-	-
Receptor	GPCR_A	–	*Npffr2*	+	+	+
Receptor	GPCR_C	LTP	*Grm8* ^b	-	+	+
Receptor	GPCR_A	–	*Mchr1*	-	+	+
Receptor	GPCR_A	–	*Gpr61*	-	+	+
Receptor	GPCR	–	*Gprc5a*	-	+	+
Receptor	Receptor	–	*Ssr2*	+	-	-
Receptor	Receptor	–	*Ifngr1*	-	+	+
Receptor	Receptor	–	*Grb2*	-	+	+
Receptor	Receptor	–	*Agtr1a*	-	+	+
Receptor	Receptor	–	*Adipor2*	-	+	+
Other	–	LTP	*Art5* ^b	+	-	-
Other	–	ARGs, LTP	*Calm3* ^ab	+	-	-
Other	–	ARGs	*Crybb2* ^a	+	-	-
Other	–	ARGs	*Prx* ^a	+	-	-
Other	–	ARGs	*Fuca1* ^a	+	-	-
Other	–	ARGs	*Cx3cl1* ^a	+	-	-
Other	–	ARGs	*Rt1.aa* ^a	+	-	-
Other	–	ARGs	*Anxa8* ^a	+	-	-
Other	–	ARGs	*Sgcg* ^a	+	-	-
Other	–	ARGs	*Ggnbp1* ^a	+	-	-
Other	–	ARGs	*Pax8* ^a	+	-	-
Other	–	ARGs	*Nfya* ^a	+	-	-
Other	–	LTP	*Sod1* ^b	+	-	+
Other	–	LTP, LTD	*Mapk3* ^bc	+	+	+
Other	–	LTP	*Stmn4* ^b	+	+	+
Other	–	ARGs, LTP, LTD	*Nrgn* ^abc	+	+	+
Other	–	ARGs	*Hyal2* ^a	+	+	+
Other	–	ARGs	*Anxa1* ^a	+	+	+
Other	–	ARGs	*Atp1b1* ^a	+	+	+
Other	–	ARGs	*Tapbp* ^a	+	+	+
Other	–	ARGs	*Rps29* ^a	+	+	+
Other	–	ARGs	*Ttc35* ^a	-	-	+
Other	–	ARGs	*Naca* ^a	-	-	+
Other	–	LTP	*Inhbc* ^b	-	+	+
Other	–	LTP	*Ppp1r2* ^b	-	+	+
Other	–	ARGs	*Aldh3a2* ^a	-	+	+
Other	–	ARGs	*Foxa2* ^a	-	+	+
Other	–	ARGs	*Tat* ^a	-	+	+
Other	–	ARGs	*H2afy* ^a	-	+	+
Other	–	ARGs	*Arhgdib* ^a	-	+	+
Other	–	ARGs	*Gdpd5* ^a	-	+	+
Other	–	ARGs	*Wdsub1* ^a	-	+	+
Other	–	ARGs	*Ect2* ^a	-	+	+
Other	–	ARGs	*Cfb* ^a	-	+	+
Other	–	ARGs	*Meox1* ^a	-	+	+
Other	–	ARGs	*Tppp3* ^a	-	+	+
Other	–	ARGs	*Vhl* ^a	-	+	+
Other	–	ARGs	*Spg7* ^a	-	+	+
Other	–	ARGs	*Dusp11* ^a	-	+	+

^aLong Term potentiation activity regulated genes (ARGs); ^bLong Term Potentiation Genes (LTP); ^cLong Term Depression Genes (LTD); G protein Coupled Receptor (GPCR); GPCR group A (GPCR_A); GPCR group C (GPCR_C); " + " Gene Expression ≥ Top 5%; "-" Gene Expression ≤ Top 50%.

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ISSN: 1471-2164

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