Table 2 Log ₂ (fold change) in helvolic acid, fumitremorgin, fumagillin and pseurotin A biosynthetic gene cluster expression in A. fumigatus wild-type and ∆ gliT exposed to exogenous gliotoxin

osc3

3.279

0.005

−6.296

0.010

cyp5081A1

2.425

0.076

−6.515

0.092

cyp5081B1

1.993

0.228

Absent^a

0.0005

sdr1

3.219

0.049

−7.163

0.293

cyp5081D1

2.633

0.200

−3.952

0.053

-

2.701

0.057

−5.964

0.063

cyp5081C1

0.470

1.000

−4.229

1.000

-

1.542

1.000

−2.941

1.000

-

0.960

0.761

−2.702

0.021

ftmA

−2.777

0.008

−6.649

0.028

ftmC

−1.278

0.205

−5.681

0.0005

ftmD

−1.263

0.181

−5.870

0.0005

ftmPT1

−1.456

0.310

−8.843

0.092

ftmE

−0.614

1.000

Absent^a

0.0005

ftmF

−0.474

0.901

−10.867

0.293

ftmG

0.611

0.844

−6.519

0.019

ftmPT2

0.581

0.844

−7.300

0.074

ftmI

0.031

0.997

−1.455

0.039

fma-PKS

0.396

0.946

−7.287

0.0005

fma-AT

0.264

0.968

−9.364

0.074

-

0.220

0.976

−7.902

0.0005

-

−0.025

0.997

−8.094

0.022

metAP/fpaII

−0.113

0.987

−5.196

0.0005

fapR/fumR

−0.284

0.957

−5.826

0.0005

-

0.265

0.969

−7.093

0.0005

psoF

0.005

0.998

−5.426

0.0005

fpaI

−0.301

0.919

−0.282

0.633

fmaE

−0.176

0.968

−0.271

0.636

fmaF

0.427

0.919

−7.258

0.0005

-

0.306

0.959

−5.649

0.007

-

−0.047

0.997

−6.780

0.002

fmaG

0.793

0.820

−8.101

0.0005

fma-TC/fmaA

0.528

0.904

−8.369

0.022

psoB

0.415

0.946

−7.450

0.0005

psoA/NRPS14

0.768

0.776

−5.792

0.0005

psoC

0.292

0.964

−7.413

0.0005

psoD

0.808

0.735

−6.778

0.0005

-

−0.271

0.965

−8.059

0.064

psoE

0.306

0.964

−8.206

0.008

-

−0.982

0.239

−1.430

0.009